CAS Insights^TM

Biomedicine, batteries, and more could be revolutionized by carbon nanotubes. See the full range of their applications.

This detailed technical report, published in collaboration with Westlake University, discusses the biomaterials landscape and how this field is rapidly changing.

Sharing new research on inverse vaccines, potential new breakthroughs in treating autoimmune diseases like multiple sclerosis, type 1 diabetes and celiac disease

See how self-healing materials that include reversible chemical bonds are reshaping wound care, drug delivery & tissue regeneration in our latest landscape analysis.

Biomarkers, personalized medicine and gene therapies are fueling research breakthroughs. Discover new treatments targeting genetics and protein buildup to manage this devastating disease.

Learn about the shift towards sustainable and natural ingredients in cosmetics, supported by data from the CAS Content Collection™.

Nanoscale materials are bridging the gap between nanotechnology and bioelectronics, paving the way for highly sensitive biosensors.

Different types of antisense oligonucleotide therapies, such as exosomes and nanoparticles, offering new hope in genetic medicine.

Learn how emerging trends in AI are impacting CBRNE threat detection and mitigation.

Unlock the potential of nanotechnology. Explore breakthroughs and challenges in energy, biomedicine, and more in our executive summary.

CAS STNext clusters can accelerate prior art search by accessing multiple curated databases, saving time and ensuring reliable results.

David Saari, Ph.D., shares his thoughts on blending science, law, and technology in IP, highlighting the competitive edge of multidisciplinary expertise.

Uncover the science behind sweeteners, their health impacts, R&D trends, and investment data.

While no cure exists for PolyQ diseases like Huntington's, new breakthroughs, therapies, and research could change that.

We speak with Mauro Mileni, Ph.D., and Chris Roth, Ph.D., about how their company is leveraging specific technology to fill an innovative drug pipeline.

Biomarkers could help doctors catch cancer earlier, cure it more frequently, and perform treatments with fewer risks.

Data-driven technologies play a pivotal role in swift analysis and quick response to chemical threats.

Pocket-sized nuclear batteries are here. Discover their potential and limitations, from powering wearables to tackling radioactive waste.

Recycling semiconductors was once a far-off dream. However, new research and technology shows that this could become reality.

Explore the science behind sweeteners, their health impact, and emerging alternatives.

Experts discuss emerging trends in immuno-oncology, data challenges, and opportunities ahead for cancer researchers.

See key insights on emerging RNA IP trends and possibilities for future innovations in this executive summary.

As antimicrobial resistance becomes a larger problem, new approaches to battling infections are emerging.

The landscape of exosomes has become highly competitive. See all the recent investments, innovations, and commercial opportunities.

See how new innovations like biorefineries, waste repurposing, and materials are reshaping the future of sustainable fertilizers.

Experts from Lawrence Livermore National Lab, Oak Ridge National Lab, The Ohio State University, and CAS discuss major research trends in 2024.

As cancer is projected to increase, finding stronger therapeutics is more urgent. Biomarkers offer a potential solution for better diagnosis and treatment.

CAS and Excelra delved into data surrounding biomarkers and their relationship to cancer to identify key targets for future study.

Immunotherapy is advancing with new approaches like CAR-T cell therapy, antibody-drug conjugates, and even checkpoint inhibitors.

AI is redefining natural product drug discovery by unlocking diverse candidates from plants, microbes, and more.

Antimicrobial-resistant infections are a global public health crisis. New solutions like AI, alternative therapeutics, and innovations in materials offer a way to fight back.

Learn how digital transformation is reducing waste and creating new revenue streams for companies as they repurpose waste byproducts.

Immuno-oncology has the potential to treat cancer without sacrificing the patient's wellbeing.

The pharma industry is tackling major drug discovery challenges in several new ways. Have they been successful?

Pharmaceutical manufacturers are investigating ways to cultivate insights from dark formulations data, turning once-hidden knowledge into drug discoveries.

With the push towards increased sustainability, here are four ways coatings manufacturers are making use of renewable feedstock for their own products.

Ozempic, Wegovy, and Mounjaro are part of a new class of semaglutides (GLP-1 receptor agonists) that help treat obesity and diabetes by regulating blood sugar and appetite.

CAS and Totus Medicines discuss how targeted covalent inhibitors are revolutionizing cancer treatments.

Single-walled carbon nanotubes have great potential in several industries from renewable energy to drug delivery.

Iddo Friedberg, an expert in protein function prediction, shares how current prediction models are performing and what current bottlenecks remain.

Covalent inhibitors were once avoided due to negative side effects, but new drugs have changed the landscape.

Drugs created with covalent inhibitors are becoming more popular than other types, owing to their unique mechanism of action.

More than 100 antibody-drug conjugates are in clinical trials. These therapeutics combine the targeting abilities of antibodies with the power of chemotherapy to change cancer treatment.

Since 2018, research interest in antibody-drug conjugates has increased exponentially, due to their potential in the fight against cancer.

CAS scientists discuss overlooked ideas that have yet to win a Nobel Prize. From OLEDs and MOFs to mRNA therapeutics and more, these ideas have reshaped science and technology.

Incomplete prior art searches and analyses can lead to costly mistakes, leaving innovations and the value of intellectual property open to huge risk.

Digital initiatives are transforming the chemical industry, allowing for faster innovation and a sustainable future.

Patentability assessments in scientific industries come with significant challenges due to their complexity. However, CAS has tools designed to address these issues.

CAS, Bayer, and Caltech explore how the gut-brain axis influences health from IBS to autism.

Strategies to unlock dark data in the pharmaceutical industry. Reveal data insights and accelerate innovation through digitization and knowledge management.

CAS, the LaJolla Institute for Immunology, and Avidity Biosciences explore the convergence of biology and chemistry in emerging therapeutics for cancer, vaccines, and more.

Digital initiatives are transforming the pharmaceutical industry, allowing for faster drug development and expanded treatment options.

Catalysts and catalysis have transformed our world, from ancient times to modern sustainability. Learn about the latest research trends and innovations.

With consumers changing their diets for personal and health reasons, innovation to increase quality and variety creates a diverse and competitive market.

Hero ingredients can help create more advanced and versatile formulations than ever before as consumers slim down their cosmetic routines.

Chemistry is powering space exploration with rocket fuel and engine technologies. Discover the advantages and challenges of using LOX/LH2 as a propellant for the Artemis mission.

Catalysts have been enabling green chemistry with applications in many industries.

ChatGPT has redefined the conversation around AI but is it right for scientific research? Find out more about the path ahead for LLMs in science.

Thanks to mRNA vaccines, which have revolutionized the fight against COVID-19, we can treat cancer by harnessing the power of the immune system.

Biomaterials like hydrogels, lipid nanoparticles, and exosomes are reshaping the landscape of drug delivery, diagnosis, and therapeutics.

Learn how leveraging patent tools and strategies can accelerate your path toward comprehensive searches and stronger insights.

Discover the latest in anti-aging treatment strategies to promote health and longevity, including stem cell therapies, hyaluronic acid, senolytics, gene therapy, and more.

Research in anti-aging treatments has reached a pivotal point. How do new treatments, drugs, and clinical trials compare to time-tested practices?

Accelerate and improve the ROI of your IP and R&D initiatives by partnering with an industry and IP expert.

Microplastics have infiltrated our entire world, even down to the water we drink and food we eat. Researchers are looking at new ways to address them.

We talk with Jefferson Parker of NullSet Informatics Solutions, about sequence analysis for drug discovery and the frontiers for AI in computational biology.

Graphene-based supercapacitor technologies are being levied for real-world applications as a battery alternative.

Induced-proximity target protein degradation (TPD) is a ground-breaking strategy in drug discovery that has emerged recently.

A successful patent landscape analysis can maximize opportunities and de-risk your company's R&D program and other initiatives.

mRNA vaccines created for COVID-19 have led to a slew of new research in mRNA therapeutics.

What is dark data, and how can it be used to unlock data insights and accelerate innovation for R&D?

Discover how advances in 3D printing materials and approaches have reshaped tissues and organ sourcing, drug delivery methods, and wound care.

Experts from Mayo Clinic, Direct Biologics, and Aruna Bio discuss how 3D bioprinting is reshaping disease treatment.

Investment in RNA has grown beyond vaccines. Cancer, infectious diseases, and even liver diseases have all been identified for RNA medicines.

Learn five ways to reduce waste and use biodegradable materials to develop sustainable sterile packaging options for medical devices.

PEG immunogenicity affects the safety and efficacy of PEGylated lipid nanoparticles for drug delivery. Much work is being done to circumvent this challenge in applying these polymers.

Learn how PEGylated lipid nanoparticles are used to deliver mRNA vaccines and other drugs, the immunogenicity concerns with vaccines, and emerging approaches on new designs to increase efficacy and safety.

PEG immunogenicity is a challenge that affects the safety and efficacy of PEGylated lipid nanoparticles for drug delivery.

We chat with Ben Taft, Sr. Director of Chemistry at Via Nova Therapeutics, about SAR studies and the possible frontiers for bioactivity data.

The gut microbiome is a complex ecosystem of trillions of bacteria that live in our digestive tracts with health benefits like immunity, improved mental health, and therapeutic options.

Created in collaboration with Bayer AG, this report discusses the latest research on microbiome-based therapies, microbiota, probiotics, and the wide range of health conditions it can influence.

This publication in the ACS Chemical Neuroscience Journal details a landscape analysis of emerging trends in the gut microbiome space.

Microplastic pollution is a global problem due to their disruption of ecosystems and their ingestion by humans and animals.

As the leading cause of drug-related deaths, fentanyl has become a public health crisis, but new breakthroughs in developing safer pain medications, reducing side effects, and developing a vaccine may reduce future deaths.

Exosomes are reshaping the future of drug delivery, therapeutics, and diagnostics. Learn about exosomes and the challenges with the technology.

3D printing has major biomedical applications. See the new technologies that are reshaping personalized healthcare.

CAS and the Chinese Academy of Sciences explore hidden connections and publication trends in synthetic organic chemistry.

This article, published in collaboration with the National Natural Science Foundation of China, the Chinese Academy of Sciences, and CAS, examines the state of global synthetic organic chemistry research with a focus on enzyme catalysis, photocatalysis, and green chemistry.

Agriculture and fertilizers have a sustainability problem. Understand emerging trends around reducing this industry's carbon emissions.

Incidents like the East Palestine chemical spill have led researchers to reevaluating the safety of transporting hazardous materials.

Exosomes have enormous potential in drug delivery, diagnostics, and more. Mayo Clinic, Direct Biologics, and Aruna Bio discuss the full landscape.

RNA medicine has spawned many new technologies and approaches. Examine market trends and where investors are funneling their money.

The expansion of exosome research has led to significant clinical advancements, and new approaches to drug delivery and diagnostics.

Discover a new approach for direct recycling that could make it possible to repair and reuse depleted batteries at a lower cost.

From prosthetic ears to artificial organs, learn about the latest trends and innovations in 3D printing in biomedicine.

We are in the middle of a 3D printing revolution, and its applications reach into biomedicine. See how it can reshape this field.

The possibilities of 3D printing in biomedicine are nearly limitless, as evidenced by this journal publication.

Nuclear energy could play a part in solving climate change, but there are still hurdles and challenges that must be overcome.

Stay ahead of the curve with the latest in emerging science and cutting-edge research that is accelerating the landscape of innovation in 2023.

Synthetic fertilizers ae valuable but leave a large carbon footprint. Sustainable fertilizers are an environmentally friendly alternative that is growing in interest.