CAS Insights^TM

Scientists are searching ways to stop the spread of COVID-19, and the ACE2 receptor is one of the most promising targets.

This blog details the recently published CAS indicator of drug innovation based on the structural novelty of new molecular entities (NMEs) which may better assess innovativeness of new drugs.

Find out how companies improve their prediction accuracy, obtain Breakthrough Technology Status and shorten the development and review time of new drugs by leveraging CAS advanced machine learning methods.

One approach that has gained momentum since the 1990s is green chemistry, a scientific field focused on "the invention, design, and application of chemical products and processes to reduce or eliminate the use and generation of hazardous substances.

Scientists at Bayer expand their understanding into new, useful chemistry by improving the predictive power of a synthesis planning model with scientist-curated reactions from CAS.

This whitepaper explores challenges and opportunities for worldwide patent offices as they seek to ensure sustainability and future growth. It focuses on the application of artificial intelligence-enabled workflow solutions to enhance productivity and patent quality.

Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional groups to explore and understand biology in living organisms.

Learn more about the scientific challenges, emerging technologies, and the financial and environmental implications for recycling lithium ion batteries.

With over 90% of the world’s plastics production requiring fossil fuels, bio-based polymers generated from renewable sources have substantial benefits over traditional plastics – from reducing CO2 emissions, increased biodegradability, and less dependence on fossil fuels. Learn more in our landscape

This insight report explores innovative research and technologies that played crucial roles in Covid-19 vaccine development.

This insight report explores innovative research and technologies that played crucial roles in Covid-19 vaccine development.

NASA’s Artemis Program has also focused attention on topics such as food safety, reliability, and nutrition in space. This blog touches on novel approaches to these problems like 3D printed space food, the use of microbes to produce nutrients, and closed-loop space farming.

It is estimated that one in five human cancers involve RAS mutations. Although once considered undruggable, this blog looks at recent advances in RAS inhibitors and emerging therapies.

The COVID pandemic revealed deficiencies in mask development and production. Innovation will be crucial in slowing the spread of new variants of the virus.

mRNA vaccines have many potential advantages over conventional vaccines in mitigating the spread and eventually ending the COVID-19 pandemic. Learn more about mRNA vaccines and how CAS is committed to supporting the fight against COVID-19.

Targeted protein degradation is a novel and quickly expanding drug discovery strategy. It is a new way of utilizing disease-causing proteins to attack severe illnesses, which has the potential to be used among more serious illnesses, such as cancer or neurodegenerative diseases.

As COVID-19 cases rise again worldwide, the Omicron subvariant BA.5 is currently the dominant strain. This blog explores some key mutations that increase transmission, evade protective antibodies, and increase the rate of (re)infection.

Artificial intelligence (AI) and machine learning have been growing exponentially over the last decade, but how has the field of Chemistry evolved with this emerging trend?

Lipid nanoparticles play critical roles in mRNA vaccines for treating COVID-19, but their use is not new. Read about past, present, and future opportunities.

The use of RNA in therapeutics has the potential to revolutionize medicine. This white paper highlights the emerging trends in the industry.

Molecular glues have been used to uncover new therapeutic agents. Because of their targeted protein degradation that holds them together, these glues have exciting potential in uncovering new drugs to fight cancer, immune diseases, and more.

This article summarizes the results of an extensive recent analysis of carbon dioxide capture, including research trends, methods employed, and storage.

The last decade has seen a dramatic shift towards RNA-based medicine. Rapid success in developing lipid-RNA nanoparticles for COVID-19 mRNA vaccines, along with several approved drugs, has propelled RNA to the forefront of pharmaceutical research and development. Explore this revolutionary trend.

We are in the midst of a therapeutic revolution, according to the authors of a recent review article in Frontiers in Bioengineering and Biotechnology.

Biopolymers, or bio-derived polymers, are generated from renewable sources, which fix atmospheric CO2 and decrease greenhouse gas emissions.