CAS InsightsTM

Accelerating your scientific progress by revealing unique connections and perspective at the intersection of science, technology, and innovation.

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Male medical worker pipetting chemical in test tube while working in laboratory
Male medical worker pipetting chemical in test tube while working in laboratory
Defining the path to TBK1 inhibition with QSAR modeling

Why are there no FDA approved TBK1 (TANK-binding kinase) inhibitors on the market, despite the key role it plays in the pathophysiology of many diseases.

Male cyclist on the road suns shiningMale cyclist on the road suns shining
Better safety, better performance: How sensors change the game

Science and wearable tech go hand in hand to provide athletes with precise, personalized information to improve their performance.

monkeyPox 博客缩略图英雄monkeyPox 博客缩略图英雄
猴痘:从科学上讲,我们应该有多担忧?

通过最近关于猴痘的头条新闻,了解更多关于研究布局、科学概况和目前可用的治疗方法的信息。对科学出版物有更深的理解,才能清晰地洞察这一新兴的新闻报道。

Inflamed knee healing, illustrationInflamed knee healing, illustration
Webinar: Emerging areas in biomaterials - Reshaping medicine and human health

Biomaterials are making an impact on health and medicine. Experts from CAS, Ortholevo, and Westlake University discuss the full landscape.

神经元和小胶质细胞神经元和小胶质细胞
罕见病和孤儿病:联合疗法可以治疗吗?

包括药物再利用、细胞疗法和基因疗法在内的联合疗法如何改善罕见病的治疗。

Two Radiologists Looking At MRI Scan On ComputerTwo Radiologists Looking At MRI Scan On Computer
Decoding neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's

Uncover the latest advancements in understanding and treating neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Huntington’s.

科学家在实验室中使用计算机科学家在实验室中使用计算机
科学搜索引擎:为什么设计它们需要艺术和科学

揭示搜索引擎功能,在广度和精确度之间取得平衡,以实现有效的科学研究。

Multi-walled Carbon NanotubeMulti-walled Carbon Nanotube
Idea in brief: Emerging trends and future opportunities for carbon nanotubes

Biomedicine, batteries, and more could be revolutionized by carbon nanotubes. See the full range of their applications.

大脑活动人脑损伤神经网络大脑活动人脑损伤神经网络
CAS 和西湖大学关于生物材料的出版物:完整报告

这份与西湖大学合作发布的详细技术报告讨论了生物材料的布局以及该领域的快速变化。

middle aged woman with mobility issuesmiddle aged woman with mobility issues
Are inverse vaccines the cure for autoimmune diseases?

Sharing new research on inverse vaccines, potential new breakthroughs in treating autoimmune diseases like multiple sclerosis, type 1 diabetes and celiac disease

氨基酸或称为蛋白质的生物分子链氨基酸或称为蛋白质的生物分子链
自修复材料领域的生物医学突破

在我们最新的布局分析中,查看包含可逆化学键的自愈材料如何重塑伤口护理、药物输送和组织再生。

Male Doctor and Patient Examining brain MRIMale Doctor and Patient Examining brain MRI
Ending Alzheimer's: Emerging trends in biomarkers, gene therapy, and more

Biomarkers, personalized medicine and gene therapies are fueling research breakthroughs. Discover new treatments targeting genetics and protein buildup to manage this devastating disease.

Organic, bio cosmetics healthy concept with Petri Dishes Organic, bio cosmetics healthy concept with Petri Dishes
Evolving beauty: The rise of sustainable and natural ingredients for cosmetics

Learn about the shift towards sustainable and natural ingredients in cosmetics, supported by data from the CAS Content Collection™.

Human brainHuman brain
From sci-fi to reality: brain-computer interfaces and the future of bioelectronics

Bioelectronics: Merging man and machine. Explore the latest advancements in brain-computer interfaces, materials, and their potential to revolutionize medicine.

baby feetbaby feet
Webinar: Nano meets medicine, biosensors redefine outcomes

Nanoscale materials are bridging the gap between nanotechnology and bioelectronics, paving the way for highly sensitive biosensors.

Molecular model of messenger ribonucleic acid mRNAMolecular model of messenger ribonucleic acid mRNA
Types of antisense oligonucleotides: Advancing therapeutic frontiers

Different types of antisense oligonucleotide therapies, such as exosomes and nanoparticles, offering new hope in genetic medicine.

Human cell and virus cellsHuman cell and virus cells
Emerging trends in global biothreat detection

Learn how emerging trends in AI are impacting CBRNE threat detection and mitigation.

A digital art image depicting a dark, circular center surrounded by a radiant halo of glowing blue and green light strands, resembling an eye or an abstract explosion. The background is a deep blue, enhancing the vibrancy of the colors.A digital art image depicting a dark, circular center surrounded by a radiant halo of glowing blue and green light strands, resembling an eye or an abstract explosion. The background is a deep blue, enhancing the vibrancy of the colors.
How nanotechnology delivers massive change in energy, biomedicine and more.

Unlock the potential of nanotechnology. Explore breakthroughs and challenges in energy, biomedicine, and more in our executive summary.

Abstract digital artwork featuring vibrant, multicolored peaks and valleys. The image showcases a dynamic blend of pink, purple, blue, and black hues, creating a visually striking and futuristic landscape with a sense of depth and movement.Abstract digital artwork featuring vibrant, multicolored peaks and valleys. The image showcases a dynamic blend of pink, purple, blue, and black hues, creating a visually striking and futuristic landscape with a sense of depth and movement.
The material difference: How biomaterials are reshaping medicine and patient outcomes

This biomaterials Insights Report explores eight key areas transforming healthcare with self-healing implants, targeted drug delivery, and more.

IP ServicesIP Services
Reaching the ‘triple point’ of patent search expertise: Practices of a successful scientific IP professional

David Saari, Ph.D., shares his thoughts on blending science, law, and technology in IP, highlighting the competitive edge of multidisciplinary expertise.

餐厅桌子上放着盐和胡椒瓶,附近还有甜味剂。餐厅桌子上放着盐和胡椒瓶,附近还有甜味剂。
揭开人造甜味剂背后的科学面纱

揭示甜味剂背后的科学、其对健康的影响、研发趋势和投资数据。

Human brainHuman brain
Can we cure Huntington's? Research trends in PolyQ and rare diseases

While no cure exists for PolyQ diseases like Huntington's, new breakthroughs, therapies, and research could change that.

Mauro and ChrisMauro and Chris
Challenges and opportunities in discovering novel drugs for “undruggable” targets

We speak with Mauro Mileni, Ph.D., and Chris Roth, Ph.D., about how their company is leveraging specific technology to fill an innovative drug pipeline.

Multi-walled Carbon NanotubeMulti-walled Carbon Nanotube
From batteries to drug delivery: Emerging applications of carbon nanotubes

Carbon nanotubes (CNTs) hold immense promise for batteries, composites, sensors, and more. Discover emerging trends on overcoming challenges and cutting edge applications.

Close up of invasive colon cancer cellsClose up of invasive colon cancer cells
16 billion reasons for hope: How biomarkers are reshaping cancer outcomes

Biomarkers could help doctors catch cancer earlier, cure it more frequently, and perform treatments with fewer risks.

Particles data waveParticles data wave
Predicting and countering chemical threats: The strategic role of data-driven technologies

Data-driven technologies play a pivotal role in swift analysis and quick response to chemical threats.

nuclear batterynuclear battery
口袋中的核能? 50年电池创新

袖珍核电池背后的科学。 从为可穿戴设备供电到处理放射性废物,探索贝塔伏特电池的潜力与局限性。

A close up of computer chipsA close up of computer chips
Science fact vs. fiction: Can we recycle semiconductors?

Recycling semiconductors was once a far-off dream. However, new research and technology shows that this could become reality.

Sugar substitute on color backgroundSugar substitute on color background
Is aspartame safe? The landscape of artificial sweeteners and sugar substitutes

Explore the science behind sweeteners, their health impact, and emerging alternatives.

白细胞白细胞
网络研讨会:癌症治疗探索的大数据见解

最近举行的癌症与大数据专家网络研讨会揭示了免疫肿瘤学的新兴趋势、数据挑战以及研究人员面临的机遇。

DNA sequencing illustrationDNA sequencing illustration
IP trends and opportunities: RNA therapeutics

See key insights on emerging RNA IP trends and possibilities for future innovations in this executive summary.

Different types of tablets in blister packaging and jars on the table.Different types of tablets in blister packaging and jars on the table.
Idea in brief: battling antibiotic resistant infections

As antimicrobial resistance becomes a larger problem, new approaches to battling infections are emerging.

A close-up image of several translucent, spherical cells with a blue outer layer and an orange-red, textured inner core. These cells appear to be floating in a blue, hazy environment, giving a microscopic view typically seen in biological studies.A close-up image of several translucent, spherical cells with a blue outer layer and an orange-red, textured inner core. These cells appear to be floating in a blue, hazy environment, giving a microscopic view typically seen in biological studies.
Keeping a finger on the pulse of exosome IP and innovation

The landscape of exosomes has become highly competitive. See all the recent investments, innovations, and commercial opportunities.

Green FertilizerGreen Fertilizer
Infographic: Sustainable crops start with green(er) fertilizers

See how new innovations like biorefineries, waste repurposing, and materials are reshaping the future of sustainable fertilizers.

Entrepreneur discussing with colleagues on video call Entrepreneur discussing with colleagues on video call
Webinar: Scientific breakthroughs and emerging trends to watch in 2024

Experts from Lawrence Livermore National Lab, Oak Ridge National Lab, The Ohio State University, and CAS discuss major research trends in 2024.

Two Asian female friends visiting her female patient in the hospital wardTwo Asian female friends visiting her female patient in the hospital ward
How biomarkers unlock faster cancer detection, improving outcomes

As cancer is projected to increase, finding stronger therapeutics is more urgent. Biomarkers offer a potential solution for better diagnosis and treatment.

Liquid based cytology microscope slide for pap smear testLiquid based cytology microscope slide for pap smear test
Biomarkers: The key to earlier cancer detection and patient outcomes

CAS and Excelra delved into data surrounding biomarkers and their relationship to cancer to identify key targets for future study.

Smart farm and Automatic robot mechanical arm harvesting vegetablesSmart farm and Automatic robot mechanical arm harvesting vegetables
Embracing the future of AI in the food industry

Discover how AI in the food industry is transforming production, innovation, and sustainability. Learn how AI can help you create smarter and more efficient food solutions.

A healthcare worker in blue protective gear, including a mask and face shield, is standing beside a seated patient in a hospital setting. The patient, with an arm cuff, is looking at a monitor displaying vital signs. Sunlight filters through large windows behind them.A healthcare worker in blue protective gear, including a mask and face shield, is standing beside a seated patient in a hospital setting. The patient, with an arm cuff, is looking at a monitor displaying vital signs. Sunlight filters through large windows behind them.
R&D Insight: Unique views into immuno-oncology

Immunotherapy is advancing with new approaches like CAR-T cell therapy, antibody-drug conjugates, and even checkpoint inhibitors.

genetic engineering and dna microarraygenetic engineering and dna microarray
人工智能在天然产物药物发现中的新兴角色

人工智能重新定义天然产物药物的发现。 了解机器学习技术如何从植物、微生物等中发掘出多种候选药物,从而加快发现速度

Antimicrobial susceptibility test Antibiogram Antibiotic resistance bacteriaAntimicrobial susceptibility test Antibiogram Antibiotic resistance bacteria
细菌与科学:与耐药性的竞赛

抗生素耐药性感染是一场全球性的公共卫生危机。 在与耐药细菌的斗争中,人们需要人工智能、替代疗法和材料创新等新型解决方案。

通往西班牙巴斯克地区圣胡安·德·加兹特卢加茨的路径通往西班牙巴斯克地区圣胡安·德·加兹特卢加茨的路径
2024 年值得关注的科学突破新兴趋势

掌握 2024 年有望加速创新并变革全球科学界的最新科学突破

磨碎的塑料薄片磨碎的塑料薄片
通过数字化转型减少浪费

了解数字化转型如何减少浪费,并通过重新利用废物副产品为公司创造新的收入来源。

insgenengsoc101791-新兴趋势免疫肿瘤学研究文章-1920x1080-Heroinsgenengsoc101791-新兴趋势免疫肿瘤学研究文章-1920x1080-Hero
免疫疗法和癌症的新兴趋势

在本文中揭示免疫肿瘤学出版物和研究领域的新趋势,确定未来的新机遇和挑战。

swirly pictureswirly picture
应对药物发现的各项挑战

The pharma industry is tackling major drug discovery challenges in several new ways. Have they been successful?

CAS data experts Mark Schmidt, Jeff Wilson, and Nicole StobartCAS data experts Mark Schmidt, Jeff Wilson, and Nicole Stobart
生命科学领域创建权威结构的挑战与机遇

在本文中,我们将与 Nicole Stobart、Jeff Wilson 和 Mark Schmidt 讨论 CAS 如何利用权威结构对生物分子进行索引。

GettyImages-1142858578_cas-Insights-Hero-ImageGettyImages-1142858578_cas-Insights-Hero-Image
通过药物制剂数据促进研发

制药制造商正在研究如何从暗制剂数据中获得见解,将曾经隐藏的知识转化为药物发现。

绿色表面上的水滴绿色表面上的水滴
可持续涂料可再生原料的四种应用

随着可持续发展理念的不断深入,涂料生产商正在通过以下 4 种方式将可再生原料用于自有产品之中。

blue light in the darkblue light in the dark
研发趋势:最大化利用暗数据,加强药物再利用

随着药物再利用市场迎来增长,制药公司正在研究如何从配方暗数据中培养见解,将曾经隐藏的见解转化为药物再利用创新。

A person sitting at a table prepping medicineA person sitting at a table prepping medicine
制药业能否战胜肥?

作为新型药物 Semaglutide(GLP-1 受体激动剂)的组成部分,探索 Ozempic、Wegovy 和 Mounjaro 如何通过调节血糖和食欲,帮助治疗肥胖症和糖尿病。

sunlight shining through the watersunlight shining through the water
光催化:更加清洁的制氢生产方式

了解光催化技术如何利用水和太阳能生产清洁氢气,以及为什么光催化技术对去碳化至关重要。 阅览有关此主题的最新研究。

a mother holds her baby girl in her arms.a mother holds her baby girl in her arms.
共价抑制剂是治愈癌症的关键吗?

了解靶向共价抑制剂如何通过激活RAS基因和PI3Kα等以往不可成药的靶点,彻底改变癌症治疗。 本次专家网络研讨会由Totus Medicines和CAS共同举办,展示了有关共价抑制剂的最新趋势和见解。

六边形结构的特写镜头。六边形结构的特写镜头。
微型技术,大有可为

了解单壁碳纳米管的新兴布局、各行各业的新应用和新方法,以及它们带来的未来机遇。

伊多·弗里德伯格的个人资料照片伊多·弗里德伯格的个人资料照片
药物发现中蛋白质功能预测的挑战与机遇

在本文中,我们将与蛋白质功能预测专家 Iddo Friedberg 一起讨论当前预测模型的性能表现等问题。

a child holding a stuffed animala child holding a stuffed animal
研发洞察:共价抑制剂的崛起

了解伊布替尼 (ibrutinib) 和阿法替尼 (afatinib) 等共价抑制剂药物如何改变癌症疗法。 在这份可共享的摘要中发现新兴机遇。

Scientists in lab coats conducting experiments in a laboratory.Scientists in lab coats conducting experiments in a laboratory.
共价抑制剂疗法的崛起

Drugs created with covalent inhibitors are becoming more popular than other types, owing to their unique mechanism of action.

病毒的特写镜头病毒的特写镜头
研发洞察:抗体偶联药物

在这份研究摘要中,您将了解抗体偶联药物如何改变癌症疗法,并发现新的机遇。

a close-up of a moleculea close-up of a molecule
揭示抗体偶联药物 (ADCs) 的潜力

了解抗体药物偶联物 (ADC) 如何以其靶向性和效力彻底改变癌症治疗。 揭示抗体偶联药物 (ADCs) 的潜力

一群人登上诺贝尔奖的舞台一群人登上诺贝尔奖的舞台
量子点荣获2023年诺贝尔化学奖

正值诺贝尔颁奖季,让我们一同探索那些尚未获得诺贝尔奖且最容易被忽视的各类见解。 从 OLED 到 MOF 再到 mRNA 疗法等多个领域,这些见解重塑了科学和技术。 加入 LinkedIn 上的对话。

由相连线网络连接的连线和点组成的网络的抽象动画。由相连线网络连接的连线和点组成的网络的抽象动画。
用于科学知识产权战略的现有技术检索与分析

不全面的现有技术检索和分析会导致代价高昂的错误,致使创新和知识产权价值面临巨大风险。 点击此处了解更多信息。

A series of connected blue dotsA series of connected blue dots
化学工业的数字化转型:迈向可持续的未来

了解数字化计划如何变革化工行业,从而实现更快的创新和可持续发展的未来。

一个男人和一个女人指着电脑屏幕一个男人和一个女人指着电脑屏幕
科技产业中的可专利性评估概览

了解科学行业中专利性评估的独特挑战,以及有助于解决此类挑战的最佳实践。

Arrow pointing from xray of a human gut to a person's brainArrow pointing from xray of a human gut to a person's brain
“肠道微生物——大脑,与健康和疾病的联系”网络研讨会

在本次网络研讨会上,CAS、拜耳和加州理工学院的专家将探讨肠道微生物群与大脑之间的奇妙联系。 了解脑肠轴如何影响从肠易激综合症 (IBS) 到自闭症患者的健康情况,以及操纵微生物组如何提供新的治疗策略。

A digital illustration featuring concentric circles with glowing blue lines and colorful particles radiating from the center, creating a dynamic, futuristic tunnel effect. The background is dark, enhancing the vibrant colors and intricate patterns.A digital illustration featuring concentric circles with glowing blue lines and colorful particles radiating from the center, creating a dynamic, futuristic tunnel effect. The background is dark, enhancing the vibrant colors and intricate patterns.
制药数据管理:揭示隐藏于黑暗中的突破性成果

制药行业的暗数据解锁策略。 通过数字化和知识管理揭示数据洞察,加速创新。

黑色背景上的蓝白线条黑色背景上的蓝白线条
CAS 研讨会探讨生物和化学在新兴疗法中的融合

了解 CAS、拉霍亚免疫学研究所 (LaJolla Institute for Immunology) 和 Avidity Biosciences 的专家如何探索生物学和化学在癌症、疫苗等新兴疗法中的融合。 此处查看回顾概要和幻灯片。

blue swirl with green lightblue swirl with green light
制药业的数字化转型:通过数字化解决方案改进研发工作

了解数字化举措如何变革制药行业,从而加快药物开发并扩大治疗选择。

Birds-eye view of two cargo shipsBirds-eye view of two cargo ships
认识催化的力量

从远古时代到现代可持续发展,探索催化剂和催化作用如何改变我们的世界。 了解这一迷人化学领域的最新研究趋势和创新。

A plant-based burger on a tableA plant-based burger on a table
通过植物肉的可持续性实现环保

随着消费者出于个人和健康原因而改变其饮食,提高质量和增加品种的创新活动开创了多样化的竞争市场。

A collection of colorful liquids in glass containers.A collection of colorful liquids in glass containers.
多功能化妆品:开发“万能”型产品

在消费者精简护肤程序的过程中,了解英雄成分如何帮助打造比以往更先进、用途更广泛的配方。

Successful rocket take off into the starry sky with the milky waySuccessful rocket take off into the starry sky with the milky way
火星在召唤,“阿尔忒弥斯”如何为火星探险之旅提供燃料?

了解化学如何通过火箭燃料和发动机技术为太空探索提供动力。 探索使用 LOX/LH2 作为阿尔忒弥斯任务推进剂的优势和挑战。

insgenengbro101249-cas-Insights-执行摘要-可持续催化剂-1920x1080-Heroinsgenengbro101249-cas-Insights-执行摘要-可持续催化剂-1920x1080-Hero
研发见解:未来的可持续催化剂

阅读本内容提要,了解催化剂如何塑造人类历史并促进可持续化学。了解使用非贵金属作为催化剂的当前研究趋势和未来机会。

资深化学教授在黑板上写作资深化学教授在黑板上写作
大语言模型是否适合科学研究?

ChatGPT 重新定义了有关人工智能的对话,但它是否适合科学研究? 了解有关大型语言模型 (LLM) 未来发展的更多信息。

INSGENENGSOC101307-mRNA-Social-Graphics-1920x1080-HeroINSGENENGSOC101307-mRNA-Social-Graphics-1920x1080-Hero
从对抗病毒到治疗肿瘤:利用 mRNA 疫苗治疗癌症

mRNA 疫苗已为抗击 COVID-19 疫情带来革命性变化,了解 mRNA 疫苗如何利用免疫系统的力量来治疗癌症。

GettyImages-1491277474_cas-Insights-Hero-ImageGettyImages-1491277474_cas-Insights-Hero-Image
探索新趋势:最值得关注的十大生物健康材料

生物材料正在重塑药物递送、诊断和治疗的格局,请详细了解该领域的十大新兴趋势。涵盖的关键材料包括水凝胶、脂质纳米颗粒、外泌体、生物墨水、可编程生物材料等。

服务轮播工作流程服务轮播工作流程
专利检索:超越基础,提高效率

了解如何利用工具和策略,加速实现全面检索和更出色的专利见解。

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重新想象衰老:探索抗衰老治疗策略的潜力

探索最新的抗衰老治疗策略,促进健康和长寿。 在我们的最新文章中了解干细胞疗法、透明质酸、抗衰老药物和基因疗法的最新研究,以及当前正在进行临床试验的管线分析。

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执行摘要:抗衰治疗的下一步是什么?

这份单页执行摘要围绕抗衰老策略和相关疗法,重点介绍了干细胞疗法、处方药和生活方式改变等方面的新兴趋势、新方法和未来机遇。 其中包括临床试验管线分析的关键收获和新兴治疗策略的前景展望。

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在科学专利检索中开展合作的原因和方法

与行业和知识产权专家开展合作,加速并提高知识产权和研发计划的投资回报率。 进一步了解 CAS 可以提供哪些帮助。

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信息图:可以对微塑料做些什么?

在我们最新的信息图中,了解微塑料是如何渗透到我们的整个世界的,以及用于去除微塑料的创新方法。

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药物发现过程中序列分析的挑战与机遇

在本篇《挑战与机遇》文章中,我们采访了生命科学数据分析专家 Jefferson Parker,双方探讨了药物发现的序列分析以及计算生物学中人工智能技术的前沿发展。

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超级电容器技术:石墨烯最终是否能够发挥该技术的全部潜力?

Graphene-based supercapacitor technologies are being levied for real-world applications as a battery alternative.

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靶向蛋白降解和诱导接近:药物发现中的分子胶布局

过去十年来,诱导接近靶向蛋白降解 (TPD) 已发展成为药物发现的突破性策略。 本 CAS 白皮书调查了研究布局和临床试验状态,并讨论了潜在未来机遇。

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通过专利布局分析,实现机会最大化

了解成功的专利布局分析如何帮助公司研发计划和其他计划实现机会最大化,同时降低风险。

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mRNA 治疗的主要最新趋势:行政摘要

本简介概述了 mRNA 研究和开发的最新趋势与新兴机遇。 其中讨论了 mRNA 技术的主要优势、仍然存在的挑战、主要参与者及其重点领域。

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在化学研发过程中解锁暗数据的力量:成功策略

化学研发中的暗数据解锁策略。通过知识管理和数据战略规划揭示数据洞察,加速创新。

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信息图:3D 打印,重塑生物医学的未来

在我们的新信息图中了解 3D 打印如何最终改变生物医学应用。看看材料和方法的进步如何重塑了以下领域:组织、移植和器官的采购、新的药物递送方法以及手术环境和伤口护理的进步。

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生物医学 3D 打印网络研讨会:CAS、哈佛大学、卡内基梅隆大学和多伦多大学

了解外泌体(即自然界的脂质纳米颗粒)如何重塑药物递送以及从癌症到心血管疾病等疾病的治疗。 查看我们最近开展的 ACS 网络研讨会,向梅奥诊所 (Mayo Clinic)、Direct Biologics 和 Aruna Bio 的专家学习。 立即观看录播视频,并阅读完整洞察报告。

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信息图:RNA的主要投资趋势和未来前景

在我们的新信息图中了解RNA疗法如何改变医学。了解这项尖端技术在癌症、传染病、肝脏和代谢性疾病中的应用、挑战和机遇。了解这个快速发展的领域中有关关键纳米颗粒、新兴类型RNA和修改序列的最新趋势和数据。

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实现可持续医疗包装的五种途径

了解五种减少废料、可生物降解的材料,为医疗器械开发可持续、无菌包装方案的途径.

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聚乙二醇化脂质纳米颗粒的终极指南

了解如何克服 PEG 免疫原性对聚乙二醇化脂质纳米颗粒药物递送安全性和有效性的影响这一挑战。 本文综述了目前解决 PEG 免疫原性的最新研究进展,从阐明抗 PEG 抗体生成的影响因素到开发新型药物载体或优化给药和剂量。

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同行评审期刊:PEG 免疫原性和疫苗安全性

这篇经过同行评审的期刊发表在《生物偶联化学》杂志上,展示了如何使用聚乙二醇化脂质纳米颗粒来输送mRNA疫苗和其他药物、疫苗的免疫原性问题以及提高疗效和安全性的新设计新方法。

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执行摘要:PEG 免疫原性的应知事项

学习如何解决聚乙二醇免疫原性,这是一项影响药物递送聚乙二醇化脂质纳米颗粒的安全性和有效性的挑战。了解这一尖端领域的最新研发趋势、市场数据和机会,包括 COVID-19 疫苗和各种利用这些纳米颗粒的当前和未来药物。

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构效关系 (SAR) 研究的挑战与机遇

在本期 CAS 系列文章《药物开发的挑战与机遇》中,我们与 Via Nova Therapeutics 的化学高级总监 Ben Taft 讨论了构效关系研究和生物活性数据的潜在前沿。

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是友非敌:肠道微生物组利于改善健康

肠道微生物组是一个由数万亿细菌组成的复杂生态系统,这些细菌存活在我们的消化道中,具有提供免疫力、改善心理健康和提供治疗选择等健康益处。 近年来,人们对微生物组疗法治疗各种疾病的潜力越来越感兴趣。 随着我们对肠道微生物组的理解不断加深,我们有望在未来几年看到微生物组疗法的更多进展。

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认识肠道微生物组的潜力

本报告对肠道微生物组进行了全面的景观分析,包括其组成、功能以及在健康和疾病中的作用。本文是与拜耳公司合作撰写的,讨论了有关基于微生物组的疗法、微生物群、益生菌及其可能影响的各种健康状况的最新研究,例如肥胖、糖尿病、炎症性肠病甚至心理健康障碍。

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同行评审出版物:新兴微生物组趋势的科学发现

这份发表在《ACS 化学神经科学》杂志上的同行评审出版物详细介绍了有关肠道微生物组领域最新发展趋势的局势分析。 它深入探讨了微生物组疗法、最新方法、新科学、临床渠道和该领域的关键参与者。

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研发洞察:微塑料的巨大影响

微塑料是一个全球性问题,可以被动物和人类摄入。它们还可以在土壤和水中聚集,而破坏坏生态系统。越南来越多的证书表明,微塑料可能对健康有害。本执行摘要重点介绍微塑料的关键来源、健康风险及可以采取的 directures micures

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在与芬太尼的对抗中取得进展

作为引起药物相关死亡的主要原因,芬太尼现已成为一场公共卫生危机,但人们在开发更安全的止痛药、减少副作用和开发疫苗方面取得了新的突破,这一进展有望减少未来的死亡人数。

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外泌体,疗法的后起之秀:信息图

外泌体正在重塑癌症及其他领域的药物输送、治疗和诊断的未来。这张全尺寸的信息图详细介绍了外泌体的关键类型、正在研究的疾病(例如癌症),并深入探讨了其强大的临床管道获得批准之前需要应对的挑战。

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研发洞察:生物医学领域的 3D 打印应用

了解生物医学领域 3D 打印应用的新兴趋势,以及重塑个性化医疗保健的全新技术。 从 3D 打印设备到定制化药物递送以及打印生物活性组织和器官,这一领域不断创新,飞速突破,对整个医疗保健行业产生了巨大影响。